ON172050_project

Development and application of the advanced chromatographic and spectrometric methods in the analysis of xenobiotics and their degradation pathways in biotic and abiotic matrices

Project financed by the Serbian Ministry of Education, Science and Technological Development

No. 172050, 2011-2014

Project Coordinator:

Prof. Dr. Biljana Škrbić, University of Novi Sad, Faculty of Technology Novi Sad

About the project

The project aim is to develop novel and advanced analytical techniques for determination of xenobiotics in the environment and human organism taken by food or medicines-herbal medicinal products. Organic and inorganic pollutants, as well active substances of medicines, including herbal medicines are the subjects of the analyze. Analytical techniques based on chromatography (UHPLC, HPLC, GC), mass spectrometry (QqQ, Orbitrap, ion trap) and optical spectroscopy (GFAAS, ICP-AES, etc.) have been used for development of reliable methods for analysis of xenobiotics in biotic and abiotic samples, including foodstuffs and medicines. The developed methods have been used to study the xenobiotic degradation in the environment, their fate in living organisms during bioaccumulation, the interactions with active substances of medicaments and herbal medicines, the metabolic pathways and therapeutic effects. Besides the analytical methods, biological, biochemical and statistical ones are also used in order to assess the health and environmental risks and to identify the pollution sources. Gained knowledge has been applied in food and pharmaceutical industry and for the environmental protection. The project results will be incorporated in 8 PhD thesis, published in international journals, presented during the conferences and at the official project site. Moreover, planned knowledge transfer activities would include organization of thematic events trainings and workshops. Two prominent researchers from abroad are included in the project team.

Participants